JNS-cover.jpgJournal of Neurological Sciences

Vol 341 | No. 1-2 | 15 June 2014 | Pages 1-190


Article TitleAuthor(s)Pages

Prevalence of migraine headache and its weight on neurological burden in Africa: A 43-year systematic review and meta-analysis of community-based studies

12 May 2014

Abstract: Background: Headache burden is not adequately explored in Africa. Here, we measured weighted migraine prevalence from community-based studies in Africa. Methods: PubMed search was employed u...

Yohannes W. Woldeamanuel, Anna P. Andreou, Robert P. Cowan 1-15

Original Articles

Article TitleAuthor(s)Pages

Cognitive dysfunction in patients with multiple sclerosis treated with different types of interferon beta: A randomized clinical trial

19 May 2014

Abstract: Background: Multiple sclerosis (MS) is a chronic autoimmune disease that can deteriorate cognitive function in at least 50% of patients even in the early stages. Objective: We conducted a th...

Naghmeh Mokhber, Amir Azarpazhooh, Elias Orouji, Stephen M. Rao, Bita Khorram, Mohammad Ali Sahraian, Mohsen Foroghipoor, Morteza Modares Gharavi, Sorayya Kakhi, Karim Nikkhah, Mahmoud Reza Azarpazhooh 16-20

Mutation analysis of PARK2 in a Uyghur family with early-onset Parkinson's disease in Xinjiang, China

14 May 2014

Abstract: Background: The PARK2 gene was recently identified as a causative gene for autosomal recessive early-onset Parkinson's disease (EOPD). Studies on how specific PARK2 mutations are manifested ...

Hongyan Li, Aishanjiang Yusufujiang, Shaliya Naser, Yi Zhu, Mayinur Maimaiti, Xiaoyan He, Juan Bu, Xuegang Meng, Mingyuan Wang, Jiang Li, Baiting Dina, Lijuan Yang, Zuhere Nayi, Hui Dang, Chengfeng Wang, Dilimulati Amiti, Asiya Aji, Nazuke Yusufu, Yan Jiao, Fengmei Duan 21-24

Association of IL6 single nucleotide polymorphisms with febrile seizures

19 May 2014

Abstract: Febrile seizures (FSs) are the most common convulsive event in children. Inflammatory elements and genetics have major roles in their pathogenesis. As of the importance of interleukin-6 (IL-...

Amin Shahrokhi, Ameneh Zare-shahabadi, Samaneh Soltani, Mahmoud Reza Ashrafi, Samaneh Zoghi, Seyed Ahmad Hosseini, Moreteza Heidari, Bahareh Yaghmaei, Babak Pourakbari, Nima Rezaei 25-28

Cross-sectional analysis of glucose metabolism in Friedreich Ataxia

12 May 2014

Abstract: Objectives: To evaluate the relationship between disease features in Friedreich ataxia and aberrant glucose metabolism. Methods: Fasting glucose, fasting insulin and random HbA1C were obtain...

Nathaniel R. Greeley, Sean Regner, Steve Willi, David R. Lynch 29-35

Cranial imaging findings in dengue virus infection

12 May 2014

Abstract: Background: The aim of this study is to evaluate cranial CT or MRI changes in dengue encephalitis and their correlation with clinical and biochemical findings. Methods: Twenty-one serologica...

Sanjeev Kumar Bhoi, Suprava Naik, Sunil Kumar, Rajendra Vishnu Phadke, Jayantee Kalita, Usha Kant Misra 36-41

Effects of deep brain stimulation in relatively young-onset multiple system atrophy Parkinsonism

15 May 2014

Abstract: Objective: The aim of this study was to analyze outcomes after 1year of bilateral STN deep brain stimulation (DBS) in relatively young-onset patients with multiple system atrophy-Parkinsonis...

Xiao-Ying Zhu, Tian-Hong Pan, William G. Ondo, Joohi Jimenez-Shahed, Yun-Cheng Wu 42-44

Transneuronal tracing of central autonomic regions involved in cardiac sympathetic afferent reflex in rats

12 May 2014

Abstract: Stimulation of cardiac afferents (CA) increased sympathetic outflow and blood pressure. The goal of the current study is to determine the central autonomic nuclei involved in the regulation ...

Juan Gao, Feng Zhang, Hai-Jian Sun, Tong-Yan Liu, Lei Ding, Yu-Ming Kang, Guo-Qing Zhu, Ye-Bo Zhou 45-51

Anatomical correlates of proprioceptive impairments following acute stroke: A case series

12 May 2014

Abstract: Background: Proprioception is the sensation of position and movement of our limbs and body in space. This sense is important for performing smooth coordinated movements and is impaired in ap...

Jeffrey M. Kenzie, Jennifer A. Semrau, Sonja E. Findlater, Troy M. Herter, Michael D. Hill, Stephen H. Scott, Sean P. Dukelow 52-61

Thalamic atrophy and cognitive impairment in clinically isolated syndrome and multiple sclerosis

12 May 2014

Abstract: Background: Cognitive deficits worsen the quality of life in multiple sclerosis and may be predicted by deep gray matter atrophy, especially thalamic atrophy. This relationship has not been ...

Tereza Štecková, Petr Hluštík, Vladimíra Sládková, František Odstrčil, Jan Mareš, Petr Kaňovský 62-68

Congenital ataxia and hemiplegic migraine with cerebral edema associated with a novel gain of function mutation in the calcium channel CACNA1A

19 May 2014

Abstract: Mutations in the CACNA1A gene, encoding the α1 subunit of the voltage-gated calcium channel CaV2.1 (P/Q-type), have been associated with three neurological phenotypes: familial and sporadic ...

Nuria García Segarra, Ivan Gautschi, Laureane Mittaz-Crettol, Christine Kallay Zetchi, Lama Al-Qusairi, Miguel Xavier Van Bemmelen, Philippe Maeder, Luisa Bonafé, Laurent Schild, Eliane Roulet-Perez 69-78

Validity and reliability of VO2-max measurements in persons with multiple sclerosis

12 May 2014

Abstract: Background: Direct measurement of whole body maximal oxygen consumption (VO2-max test) is considered the gold standard when assessing cardiorespiratory fitness. Nonetheless, the validity and...

Martin Langeskov-Christensen, Daniel Langeskov-Christensen, Kristian Overgaard, Andreas Buch Møller, Ulrik Dalgas 79-87

Spectrum of central nervous system disorders in hospitalized HIV/AIDS patients (2009–2011) at a major HIV/AIDS referral center in Beijing, China

15 May 2014

Abstract: Objective: To describe the spectrum of central nervous system (CNS) disorders and the contribution of neurological immune reconstitution inflammatory syndrome (IRIS) in hospitalized HIV/AIDS...

Lili Dai, Supriya D. Mahajan, Caiping Guo, Tong Zhang, Wen Wang, Tongzeng Li, Taiyi Jiang, Hao Wu, Ning Li 88-92

The incidence of critical-illness-related-corticosteroid-insufficiency is associated with severity of traumatic brain injury in adult rats

12 May 2014

Abstract: Traumatic brain injury (TBI) causes deleterious critical-illness-related-corticosteroid-insufficiency (CIRCI), leading to high mortality and morbidity. However, the incidence of CIRCI follow...

Xin Chen, Zilong Zhao, Yan Chai, Lanlan Luo, Rongcai Jiang, Jianning Zhang 93-100

Cannabinoid type 2 receptor stimulation attenuates brain edema by reducing cerebral leukocyte infiltration following subarachnoid hemorrhage in rats

12 May 2014

Abstract: Early brain injury (EBI), following subarachnoid hemorrhage (SAH), comprises blood–brain barrier (BBB) disruption and consequent edema formation. Peripheral leukocytes can infiltrate the inj...

Mutsumi Fujii, Prativa Sherchan, Paul R. Krafft, William B. Rolland, Yoshiteru Soejima, John H. Zhang 101-106

Matrix metalloproteinase-1 and matrix metalloproteinase-12 gene polymorphisms and the risk of ischemic stroke in a Tunisian population

16 May 2014

Abstract: Matrix metalloproteinases (MMPs) play an important role in early atherosclerosis, extracellular matrix remodeling, plaque rupture and myocardial infarction. MMP gene polymorphisms contribute...

Khouloud Chehaibi, Mohamed Yahia Hrira, Samir Nouira, Faouzi Maatouk, Khaldoun Ben Hamda, Mohamed Naceur Slimane 107-113

The effect of hyperbaric oxygen on intracephalic angiogenesis in rats with intracerebral hemorrhage

15 May 2014

Abstract: Healthy SD rats were randomly divided into 3 groups as sham operation (group A), ICH (group B), and HBO2 (group C). The behavioral change and angiogenesis in brain tissue of rats in each gro...

Zheng-Rong Peng, A-Li Yang, Qi-Dong Yang 114-123

Blood transfusion-related posterior reversible encephalopathy syndrome

12 May 2014

Abstract: Neurological complications have rarely been described after blood transfusion. Posterior reversible encephalopathy syndrome (PRES) is a recently recognized entity affecting predominantly the...

Zhen-Yu Zhao, Feng He, Pei-Hong Gao, Jian-Zhong Bi 124-126

An open labeled randomized controlled trial of pregabalin versus amitriptyline in chronic low backache

12 May 2014

Abstract: Background: There is no head on comparison of amitriptyline (AMT) and pregabalin (PG) in relieving pain and disability in chronic low backache (CLBA). This randomized controlled trial report...

J. Kalita, A.K. Kohat, U.K. Misra, S.K. Bhoi 127-132

IL-17F but not IL-17A gene polymorphism confers risk to multiple sclerosis in a Chinese Han population

12 May 2014

Abstract: Interleukin-17 has been shown to be associated with autoimmune disease. The aim of the current study is to investigate the potential association of IL-17 polymorphisms with multiple sclerosi...

Shunxian Wang, Hong Zhai, Yijun Su, Yinxu Wang 133-136

Clinical and magnetic resonance imaging characteristics of tubercular ventriculitis: An under-recognized complication of tubercular meningitis

19 May 2014

Abstract: Background: Ventriculitis also referred as ependymitis or ventricular empyema is a known complication of pyogenic meningitis. Despite high incidence of tubercular meningitis in developing co...

Prabhat Singh, Vimal K. Paliwal, Zafar Neyaz, Arun K. Srivastava, Ritu Verma, Suyash Mohan 137-140

Association of intracranial pressure with outcome in comatose patients with intracerebral hemorrhage

16 May 2014

Abstract: Background: Therapeutic targets for intracranial pressure (ICP) in patients with severe intracerebral hemorrhage (ICH) are approximated from data of traumatic brain injury. However, specific...

Marek Sykora, Sahra Steinmacher, Thorsten Steiner, Sven Poli, Jennifer Diedler 141-145

Neuroprotective effect of cathodal transcranial direct current stimulation in a rat stroke model

19 May 2014

Abstract: Experimental focal brain ischemia generates in the penumbra recurrent depolarizations which spread across the injured cortex inducing infarct growth. Transcranial direct current stimulation ...

Francesca Notturno, Marta Pace, Filippo Zappasodi, Etrugul Cam, Claudio L. Bassetti, Antonino Uncini 146-151

Lateralization of temporal lobe epilepsy using a novel uncertainty analysis of MR diffusion in hippocampus, cingulum, and fornix, and hippocampal volume and FLAIR intensity

19 May 2014

Abstract: Purpose: To analyze the utility of a quantitative uncertainty analysis approach for evaluation and comparison of various MRI findings for the lateralization of epileptogenicity in mesial tem...

Mohammad-Reza Nazem-Zadeh, Jason M. Schwalb, Kost V. Elisevich, Hassan Bagher-Ebadian, Hajar Hamidian, Ali-Reza Akhondi-Asl, Kourosh Jafari-Khouzani, Hamid Soltanian-Zadeh 152-161

Prevalence of MR imaging abnormalities in vitamin B12 deficiency patients presenting with clinical features of subacute combined degeneration of the spinal cord

19 May 2014

Abstract: Background and aims: Subacute combined degeneration (SACD) of the spinal cord, characterized by degeneration of lateral and posterior columns, is often found in vitamin B12 deficiency. Our a...

Krishan K. Jain, Hardeep S. Malhotra, Ravindra K. Garg, Pradeep K. Gupta, Bhaswati Roy, Rakesh K. Gupta 162-166

Short Communications

Article TitleAuthor(s)Pages

Clinical and MRI correlates of disease progression in a case of nonfluent/agrammatic variant of primary progressive aphasia due to progranulin (GRN) Cys157LysfsX97 mutation

12 May 2014

Abstract: Little is known about the longitudinal changes of brain damage in patients with sporadic nonfluent/agrammatic variant of primary progressive aphasia (nfvPPA) and in progranulin (GRN) mutatio...

Francesca Caso, Federica Agosta, Giuseppe Magnani, Sebastiano Galantucci, Edoardo G. Spinelli, Daniela Galimberti, Andrea Falini, Giancarlo Comi, Massimo Filippi 167-172

A novel ferritin light chain mutation in neuroferritinopathy with an atypical presentation

12 May 2014

Abstract: Neuroferritinopathy or hereditary ferritinopathy is an inherited neurodegenerative disease caused by mutations in ferritin light chain (FTL) gene. The clinical features of the disease are hi...

Katsuya Nishida, Holly J. Garringer, Naonobu Futamura, Itaru Funakawa, Kenji Jinnai, Ruben Vidal, Masaki Takao 173-177

Primary neurolymphomatosis diagnosis and treatment: A retrospective study

14 May 2014

Abstract: Background: To discuss the therapeutic approach for primary neurolymphomatosis. Methods: We report all primary neurolymphomatosis cases referred to our institution, with descriptions of clin...

S. Lagarde, E. Tabouret, M. Matta, J. Franques, S. Attarian, J. Pouget, A. Maues De Paula, D. Figarella-Branger, P. Dory-Lautrec, O. Chinot, M. Barrié 178-181

Diagnostic value of MR imaging in the Lewis–Sumner syndrome: A case series

12 May 2014

Abstract: Lewis–Sumner syndrome (LSS) is considered a variant of chronic inflammatory demyelinating polyneuropathy (CIDP), which is more frequently described with exclusive upper limb involvement. The...

Yusuf A. Rajabally, Michael J. Knopp, Darren Martin-Lamb, John Morlese 182-185

Increased serum levels of adiponectin in migraine

12 May 2014

Abstract: Background and objectives: Inflammatory mediators, including adipokines, have been studied in migraine pathophysiology; however, their role is not yet well established. The aim of the presen...

Halina Duarte, Antonio L. Teixeira, Natália P. Rocha, Renan B. Domingues 186-188

Hemichorea in a patient with diabetic ketoacidosis

23 May 2014

Abstract: Background: Chorea is a common presenting feature of metabolic disorders, including nonketotic hyperglycemia in patients with type 2 diabetes mellitus, but rarely has been reported in diabet...

Ahmed M. Yassin, Sheetal Shroff, Shreshta D. Patel, Asif M. Paker, Megan A. Berman, George R. Jackson 189-191

An adult case of cerebral malakoplakia successfully cured by treatment with antibiotics, bethanechol and ascorbic acid

19 May 2014

Abstract: Cerebral malakoplakia is a very rare chronic inflammatory disease. We herein report the case of a 49-year-old female who presented with a slowly progressive speech disturbance and right hemi...

Hirotaka Fudaba, Hiroshi Ooba, Tatsuya Abe, Tohru Kamida, Yukihiro Wakabayashi, Hirofumi Nagatomi, Minoru Fujiki 192-196

Longterm deep brain stimulation withdrawal: Clinical stability despite electrophysiological instability

19 May 2014

Abstract: Deep brain stimulation (DBS) is a powerful treatment option for movement disorders, including severe generalised dystonia. After several years of treatment, cases have been reported in which...

Diane Ruge, Laura Cif, Patricia Limousin, Victoria Gonzalez, Xavier Vasques, Philippe Coubes, John C. Rothwell 197-199

Letters to the Editor

Article TitleAuthor(s)Pages

Neuroimaging findings in Hunter disease

12 May 2014

A 36year-old man previously diagnosed with Hunter disease (; panels A & B) on the basis of biochemical and molecular genetic findings was presented with gait impairment and progressive hand weakne...

Georgios Tsivgoulis, Matilda A. Papathanasiou, Christos Krogias, Panagiotis Kokotis, Maria Chondrogianni, Chrissoula Liantinioti, Sokratis G. Papageorgiou, Helen Michelakakis, Leonidas Stefanis 200-201

Delayed intracranial hemorrhage after deep brain stimulation in two Parkinson's disease patients

19 May 2014

Deep brain stimulation (DBS) is a widely accepted procedure used to treat patients with Parkinson's disease . Although age, sex, blood pressure, aspirin use, selection of anatomical targets, injury du...

Eun Joo Chung, Moo Seong Kim, Sang Jin Kim 202-203

New IDH1 I113T mutation associated with BRAF V600E mutation: New driver of gliomagenesis?

19 May 2014

Abstract: Background: IDH mutations and BRAF mutations are classically mutually exclusive and usually associated with infiltrative or circumscribed gliomas and glioneuronal tumors respectively. Case r...

E. Tabouret, F. Fina, F. Vincentelli, I. Nanni, D. Figarella-Branger 204-206

Book Review

Article TitleAuthor(s)Pages

Book review

12 May 2014

The second edition is an impressive compilation of recent advances in the neurosciences of the frontal lobes. The new volume elegantly merges cognitive neuroscience, neurochemistry, social cognition, ...

Dolly Berla, Arnulf H. Koeppen 207