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World Neurology

  • Early Endeavors to Build a CT Scan: The Ukraine Pioneers 8
    By Peter J. Koehler

    Some years ago, I presented a lecture on the history of CT and MR at the History of Neurology course of the American Academy of Neurology (2018). Soon after the invention of X-rays by Wilhelm Conrad Röntgen (1845-1923) in 1895, two steps needed to be made to improve brain imaging, notably the introduction of contrast enhancement and the production of 3D images.
  • American Epilepsy Society Announces Position Statement on Valproate Use in Women of Childbearing Potential ⧉

    The American Epilepsy Society (AES) president, R. Edward Hogan, MD, recently shared important information about the serious risks associated with use of valproate (valproic acid, divalproex) by women of childbearing potential, as highlighted in the updated AES Position Statement on the Use of Valproate by Women of Childbearing Potential.

 

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  • Motor cortical plasticity and its correlation with motor symptoms in Parkinson's disease ⧉

    VOLUME 29, DECEMBER 2022, 100422

    The relationship between abnormal cortical plasticity and parkinsonian symptoms remains unclear in Parkinson's disease (PD).

    We studied the relationship between their symptoms and degree of Long-term potentiation (LTP)-like effects induced by quadripulse magnetic stimulation (QPS) over the primary motor cortex, which has a small inter-individual variability in humans.

    Our results suggest that motor cortical plasticity relate with mechanisms underlying bradykinesia and rigidity in the upper limb muscles. LTP induced by QPS may be used as an objective marker of parkinsonian symptoms.

  • Discussing brain magnetic resonance imaging results for neonates with hypoxic-ischemic encephalopathy treated with hypothermia: A challenge for clinicians and parents⧉

    VOLUME 29, DECEMBER 2022, 100424

    Clinicians use brain magnetic resonance imaging (MRI) to discuss neurodevelopmental prognosis with parents of neonates with hypoxic-ischemic encephalopathy (HIE) treated with therapeutic hypothermia (TH).

    This study investigates how clinicians and parents discuss these MRI results in the context of HIE and TH and how these discussions could be facilitated and more meaningful for parents.

    Discussing brain MRI results for neonates with HIE treated with TH are challenging tasks for clinicians and daunting moments for parents.


 

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