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Christina Briscoe Abath, MD, and Edmkeryma Acevedo, MD
Partnerships could lead to new treatments and improved patient care.
Although it has gone by many other names, infantile epileptic spasms syndrome (IESS) has been described since 1841. It is the most common infantile-onset epilepsy syndrome, and first-line treatments are over 40 years old. There has been consensus about the initial treatment for over a decade, as well as recognition that the lead time to standard treatment affects long-term developmental outcomes. Treatment initiation of first- line therapy is considered a priority for the clinical team.
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By Peter J. Koehler
A look back at the relationship between electricity and the brain on the 100th anniversary of the first human EEG recording. This year marks the centennial of the first registration of a human electroencephalogram (EEG). Why is it that just a few hundred years ago physicians were still thinking in terms of animal spirits (spiritus animalis) flowing through cerebral ventricles and hollow nerves, when today we can create brain- computer interfaces to help disabled persons control their wheelchairs?
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Gouider R, Souissi A, Mrabet S, Gharbi A, Abida Y, Kacem I, Gargouri-Berrechid A.
Journal of the Neurological Sciences. 2024 Aug 6:123161.
Multiple Sclerosis (MS) is a complex neurological disease which prevalence is increasing worldwide. The impact of environmental factors on MS susceptibility has already been defined and highlighted in many previous reports, particularly vitamin D or ultraviolet B light exposure, Epstein–Barr virus (EBV) infection, obesity, and smoking.
There is increasing evidence that environmental and lifestyle factors are not only important in triggering MS but are also implicated in MS progression.
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Sharifi P, Rezaeimanesh N, Moradi A, Moghadasi AN.
eNeurologicalSci. 2024 Jun 12:100511.
Patients with multiple sclerosis (MS) are at higher risk of having infections due to receiving disease modifying therapies. The current study was conducted among Iranian MS patients who had experienced at least one episode of COVID-19 infection in order to evaluate the effects of COVID-19 vaccination on symptoms of their infection. Data on demographic information, MS characteristics, COVID-19 infection details, and vaccination status were collected. Statistical analyses, were performed to evaluate the association between vaccination and symptoms of COVID-19 infection.
COVID-19 vaccination can reduce the incidence of respiratory symptoms and headaches in MS patients during COVID-19 infection episodes. Additionally, patients who are receiving immunosuppressive drugs may benefit from COVID-19 vaccination.
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Galetaki D, Szymczuk V, Shi M, Merchant N
eNeurologicalSci. 2024 Jun 15:100513.
Glucocorticoids are standard of care for patients with Duchenne muscular dystrophy (DMD). Although prolonged exposure is associated with multiple endocrine side effects, current guidelines related to monitoring and management of endocrinopathies are suboptimal. We aim to explore community perceptions of endocrine related complications in patients with DMD, assess current level of understanding, and desire for further education.
A 31-item online survey was sent through Parent Project to Muscular Dystrophy (PPMD) to Duchenne Registry members to be completed by patients or their caretakers.
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