Journal of Neurological Sciences
Vol 340 | No. 1-2 | 15 June 2014 | Pages 1-248
Editorials |
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| Article Title | Author(s) | Pages |
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A raging fire in acute lacunar stroke: Inflammation, blood–brain barrier dysfunction and the origin of cerebral microbleeds21 March 2014 Cerebral microbleeds (CMBs) detected on T2*-weighted gradient-recalled echo or susceptibility-weighted MRI sequences have sparked scientific and clinical interest over the past 15years . Extensive res... |
Andreas Charidimou, David J. Werring | 1-2 |
New pathways for an old molecule: The role of the Na +–K + ATPase pump in peripheral neuropathy24 March 2014 Life began in the ocean. The first organisms, just single cells, needed a way to keep their cytoplasm inside a cell membrane less salty than the surrounding seawater. This was done by some of the firs... |
Craig W. Stevens | 3-4 |
Reviews |
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| Article Title | Author(s) | Pages |
Body mass index and dietary intervention: Implications for prognosis of amyotrophic lateral sclerosis17 March 2014 Abstract: Amyotrophic lateral sclerosis (ALS) is an adult onset, neurodegenerative disease that is characterized by the loss of upper (corticospinal) and lower motor neurons. ALS is a multifactorial d... |
S.T. Ngo, F.J. Steyn, P.A. McCombe | 5-12 |
Positive signs of functional weakness21 March 2014 Abstract: Functional (conversion) neurological symptoms represent as one of the most common situations faced by neurologists in their everyday practice. Among them, acute or subacute functional weakne... |
Lucio Tremolizzo, Emanuela Susani, Michele Augusto Riva, Giancarlo Cesana, Carlo Ferrarese, Ildebrando Appollonio | 13-18 |
Dengue-associated hypokalemic paralysis: Causal or incidental?31 March 2014 Abstract: Dengue-associated hypokalemic paralysis is considered an important but under-emphasized neuromuscular complication of dengue virus infection. Review of the published literature reveals that ... |
Hardeep Singh Malhotra, Ravindra Kumar Garg | 19-25 |
Paradoxical reaction in HIV negative tuberculous meningitis31 March 2014 Abstract: This review focusses on paradoxical reactions occurring during the treatment of tuberculous meningitis (TBM) in human immunodeficiency virus-negative cases. A paradoxical reaction is defined... |
Ravindra Kumar Garg, Hardeep Singh Malhotra, Neeraj Kumar | 26-36 |
Original Articles |
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| Article Title | Author(s) | Pages |
Increased cerebrospinal fluid protein and motor conduction studies as prognostic markers of outcome and nerve ultrasound changes in Guillain–Barré syndrome06 March 2014 Abstract: Objective: Our study examined the prognostic role of increased cerebrospinal fluid protein and motor conduction studies on outcome and nerve ultrasound changes in Guillain–Barré syndrome (GB... |
Antonios Kerasnoudis, Kalliopi Pitarokoili, Volker Behrendt, Ralf Gold, Min-Suk Yoon | 37-43 |
Intravenous thrombolysis with rt-PA for acute ischemic stroke within 24
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Piotr Sobolewski, Waldemar Brola, Małgorzata Wiszniewska, Wiktor Szczuchniak, Małgorzata Fudala, Mariusz Domagalski, Monika Śledzińska-Dźwigał | 44-49 |
Accelerometer cut-points derived during over-ground walking in persons with mild, moderate, and severe multiple sclerosis13 March 2014 Abstract: Background: There has been increased interest in objectively quantifying time spent in moderate-to-vigorous physical activity (MVPA) using accelerometry as an outcome among persons with mult... |
Brian M. Sandroff, Barry J. Riskin, Stamatis Agiovlasitis, Robert W. Motl | 50-57 |
Altered spontaneous activity in treatment-naive childhood absence epilepsy revealed by Regional Homogeneity17 April 2014 Abstract: Purpose: To explore the differences in regional spontaneous activities throughout the whole brain by the Regional Homogeneity (ReHo) method in untreated childhood absence epilepsy (CAE), in ... |
Tianhua Yang, Zhijia Fang, Jiechuan Ren, Fenglai Xiao, Qifu Li, Ling Liu, Du lei, Qiyong Gong, Dong Zhou | 58-62 |
SMN1 duplications contribute to sporadic amyotrophic lateral sclerosis susceptibility: Evidence from a meta-analysis13 March 2014 Abstract: Objective: To investigate the association between SMN1 and SMN2 copy number variations (CNVs) and sporadic amyotrophic lateral sclerosis (SALS) by a meta-analysis. Methods: Through searching... |
Xue-Bin Wang, Ning-Hua Cui, Jia-Jia Gao, Xue-Ping Qiu, Fang Zheng | 63-68 |
Multiple sclerosis is associated with high trait anger: A case–control study13 March 2014 Abstract: Introduction: In recent years there has been a focus on health-related quality of life in multiple sclerosis (MS) and in particular the importance of non-motor problems such as fatigue, pain... |
Julián Benito-León, Andrés Labiano-Fontcuberta, Alex J. Mitchell, Moreno-García Sara, Pablo Martínez-Martín | 69-74 |
Plasma S100A12 is associated with functional outcome after ischemic stroke: Research for Biomarkers in Ischemic Stroke14 March 2014 Abstract: Background: Ischemic stroke is accompanied by an inflammatory response, which exacerbates brain injury and deteriorates functional outcome. S100A12 is expressed abundantly in granulocytes, a... |
Yoshinobu Wakisaka, Tetsuro Ago, Masahiro Kamouchi, Jyunya Kuroda, Ryu Matsuo, Jun Hata, Seiji Gotoh, Tetsu Isomura, Hideto Awano, Kazuo Suzuki, Kenji Fukuda, Yasushi Okada, Yutaka Kiyohara, Hiroaki Ooboshi, Takanari Kitazono, on behalf of the REBIOS Investigators | 75-79 |
The effect of topiramate and lamotrigine on rat bone mass, structure and metabolism17 March 2014 Abstract: There is only limited data concerning the effect of the newer antiepileptic drugs on bone. The objective of this study was to determine the effect of topiramate (TPM) and lamotrigine (LTG) m... |
Julius Simko, Sona Fekete, Iveta Gradosova, Jana Malakova, Helena Zivna, Martin Valis, Vladimir Palicka, Pavel Zivny | 80-85 |
Whole-exome sequence analysis of ataxia telangiectasia-like phenotype17 March 2014 Abstract: A number of diseases exhibit neurodegeneration with/without additional symptoms such as immunodeficiency, increased cancer risk, and microcephalus. Ataxia telangiectasia and Nijmegen breakag... |
Setsuko Hasegawa, Kohsuke Imai, Kenichi Yoshida, Yusuke Okuno, Hideki Muramatsu, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Seiji Kojima, Seishi Ogawa, Tomohiro Morio, Shuki Mizutani, Masatoshi Takagi | 86-90 |
Genotype–phenotype correlation in a cohort of paroxysmal kinesigenic dyskinesia cases24 March 2014 Abstract: Background: Recently, PRRT2 gene mutations have been identified as a causative factor of paroxysmal kinesigenic dyskinesia (PKD). However, evidence is still lacking with respect to the genot... |
Cheng-yuan Mao, Chang-he Shi, Bo Song, Jun Wu, Yan Ji, Jie Qin, Yu-sheng Li, Jing-jing Wang, Dan-dan Shang, Shi-lei Sun, Yu-ming Xu | 91-93 |
Congenital fiber type disproportion myopathy caused by LMNA mutations18 March 2014 Abstract: A boy, who had shown muscle weakness and hypotonia from early childhood and fiber type disproportion (FTD) with no dystrophic changes on muscle biopsy, was initially diagnosed as having cong... |
Sachiko Kajino, Kayo Ishihara, Kanako Goto, Keiko Ishigaki, Satoru Noguchi, Ikuya Nonaka, Makiko Osawa, Ichizo Nishino, Yukiko K. Hayashi | 94-98 |
Ehlers–Danlos Syndrome and Postural Tachycardia Syndrome: A relationship study31 March 2014 Abstract: Objective: This study examines a possible relationship between Ehlers–Danlos Syndrome (EDS) and Postural Tachycardia Syndrome (POTS). Design/methods: We retrospectively reviewed 109 medical ... |
Daniel Wallman, Janice Weinberg, Anna Depold Hohler | 99-102 |
Clinical and biological changes under treatment with lithium carbonate and valproic acid in sporadic amyotrophic lateral sclerosis25 March 2014 Abstract: The aim of this study was to evaluate the ability of lithium carbonate and valproate cotreatment to modify the survival rate and functional score of patients with definite sporadic amyotroph... |
Marie-Catherine Boll, Leo Bayliss, Steven Vargas-Cañas, Jorge Burgos, Sergio Montes, Guillermo Peñaloza-Solano, Camilo Rios, Mireya Alcaraz-Zubeldia | 103-108 |
Cryptococcal meningitis in a multiple sclerosis patient taking natalizumab31 March 2014 Abstract: Importance: Natalizumab was approved in 2004 by the US Food and Drug Administration (US-FDA) for treatment of multiple sclerosis (MS), however it was temporarily withdrawn after its use was ... |
Reuben Mari Valenzuela, John H. Pula, Dennis Garwacki, John Cotter, Jorge C. Kattah | 109-111 |
Neuroprotective effects of JGK-263 in transgenic SOD1-G93A mice of amyotrophic lateral sclerosis31 March 2014 Abstract: Background: Glycogen synthase kinase-3β (GSK-3β) activity plays a central role in motor neuron degeneration. GSK-3β inhibitors have been shown to prolong motor neuron survival and suppress d... |
Suk-Won Ahn, Gye Sun Jeon, Myung-Jin Kim, Jee-Heun Shon, Jee-Eun Kim, Je-Young Shin, Sung-Min Kim, Seung Hyun Kim, In-Hae Ye, Kwang-Woo Lee, Yoon-Ho Hong, Jung-Joon Sung | 112-116 |
Cytokine production profiles in chronic relapsing–remitting experimental autoimmune encephalomyelitis: IFN-γ and TNF-α are important participants in the first attack but not in the relapse21 March 2014 Abstract: Multiple sclerosis (MS) is a chronic demyelinating disease often displaying a relapsing–remitting course of neurological manifestations that is mimicked by experimental autoimmune encephalom... |
Yoshihiko Hidaka, Yuji Inaba, Kazuyuki Matsuda, Makoto Itoh, Tomoki Kaneyama, Yozo Nakazawa, Chang-Sung Koh, Motoki Ichikawa | 117-122 |
Reliability of a cognitive endpoint for use in a multiple sclerosis pharmaceutical trial24 March 2014 Abstract: Objective: Determine reliability and basic psychometric properties of a composite cognitive endpoint, MS-COG, for monitoring change in cognitive function in MS drug trials. Background: 50% o... |
David M. Erlanger, Tanya Kaushik, Lauren S. Caruso, Ralph H.B. Benedict, F.W. Foley, Jeffrey Wilken, Diego Cadavid, John DeLuca | 123-129 |
Magnetic resonance imaging reveals Creutzfeldt–Jakob disease in a patient with apparent dementia with Lewy bodies31 March 2014 Abstract: The differential diagnosis of dementia with Lewy bodies (DLB) and sporadic Creutzfeldt–Jakob disease (CJD) may be challenging. Patients with the original diagnosis of possible CJD may occasi... |
Georgios Tsivgoulis, Anastasios Bonakis, Matilda A. Papathanasiou, Maria Chondrogianni, Sokratis G. Papageorgiou, Konstantinos Voumvourakis, Leonidas Stefanis | 130-132 |
The ratio of d-dimer to brain natriuretic peptide may help to differentiate between cerebral infarction with and without acute aortic dissection20 March 2014 Abstract: Background: Previous studies reported that the plasma d-dimer level reflects the activity of thrombus formation in the left atrium of patients with acute cerebral infarction and acute aortic... |
Toshiyuki Okazaki, Yoko Yamamoto, Keishi Yoda, Shinji Nagahiro | 133-138 |
Regulation and pharmacological blockade of sodium-potassium ATPase: A novel pathway to neuropathy24 March 2014 Abstract: Inflammation causes upregulation of NaV1.7 sodium channels in the associated dorsal root ganglia (DRG). The resultant increase in sodium influx must be countered to maintain osmotic homeosta... |
Dennis Paul, R. Denis Soignier, Lerna Minor, Hui Tau, Emel Songu-Mize, Harry J. Gould, | 139-143 |
Determinants of the quality of life in Parkinson's disease: Results of a cohort study from Southwest China27 March 2014 Abstract: Background: The determinants of the quality of life (QoL) of patients with Parkinson's disease (PD) in Chinese population remain largely unknown. Methods: A total of 649 PD patients from Sou... |
Ying Wu, Xiao Yan Guo, Qian Qian Wei, Wei Song, Ke Chen, Bei Cao, Ru Wei Ou, Bi Zhao, Hui Fang Shang | 144-149 |
Clinico-radiological predictors of vascular cognitive impairment (VCI) in patients with stroke: A prospective observational study31 March 2014 Abstract: Background and purpose: Cognitive dysfunction occurs commonly following stroke and varies in severity. This study was aimed to determine the clinical, neuro-imaging, laboratory predictors of... |
Tejendra Sukdeo Chaudhari, Rajesh Verma, Ravindra Kumar Garg, Manish Kumar Singh, Hardeep Singh Malhotra, Praveen kumar Sharma | 150-158 |
Glibenclamide treatment modulates the expression and localization of myosin-IIB in diabetic rat brain10 April 2014 Abstract: Background: Myosin-IIB is a non-muscle isoform in the brain with increased expression in the brains of diabetic rats. Chronic hyperglycemia caused by diabetes can impair learning and memory.... |
Alice Vieira da Costa, Luciana Karen Calábria, Paula de Souza Santos, Luiz Ricardo Goulart, Foued Salmen Espindola | 159-164 |
CTP infarct core may predict poor outcome in stroke patients treated with IV t-PA01 April 2014 Abstract: Background: Computerized tomography perfusion (CTP) has been widely studied in assessing physiological brain tissue parameters in patients with acute ischemic stroke (AIS). The utility of CT... |
Tzu-Ching Wu, Clark Sitton, Andrew Potter, Ritvij Bowry, Preeti Sahota, Chunyan Cai, Peng Hui, Zhongxue Chen, Nicole Gonzales, Andrew Barreto, George Lopez, James C. Grotta, Sean I. Savitz | 165-169 |
The lateralized smell test for detecting Alzheimer's disease: Failure to replicate16 April 2014 Abstract: Objectives: A widely publicized study by Stamps, Bartoshuk and Heilman (2013) reported that a simple measure of left:right naris differences in the ability to detect the odor of peanut butte... |
Richard L. Doty, Edgardo A. Bayona, Daniel S. Leon-Ariza, Juan Cuadros, Inna Chung, Britney Vazquez, Fidias E. Leon-Sarmiento | 170-173 |
An 18F-FDG PET study of cervical muscle in parkinsonian anterocollis11 April 2014 Abstract: The underlying etiology of parkinsonian anterocollis has been the subject of recent debate. The purpose of this study is to test the hypothesis that anterocollis in parkinsonian syndromes is... |
Gonzalo J. Revuelta, Jaime Montilla, Michael Benatar, Alan Freeman, Thomas Wichmann, Hyder A. Jinnah, Mahlon R. DeLong, Stewart A. Factor | 174-177 |
Modulation of alertness by sustained cognitive demand in MS as surrogate measure of fatigue and fatigability04 April 2014 Abstract: Objective: This study used reaction time (RT) as an objective marker of cognitive fatigue and fatigability in patients with multiple sclerosis (MS). Method: RT was measured in fifteen health... |
Micha Neumann, Annette Sterr, Dolores Claros-Salinas, Rolf Gütler, Rolf Ulrich, Christian Dettmers | 178-182 |
Clinico-pathological factors influencing surgical outcome in drug resistant epilepsy secondary to mesial temporal sclerosis02 April 2014 Abstract: Background: Mesial temporal sclerosis (MTS) is the most common cause of drug resistant epilepsy amenable for surgical treatment and seizure control. Methods: This study analyzed the outcome ... |
B.V. Savitr Sastri, A. Arivazhagan, Sanjib Sinha, Anita Mahadevan, R.D. Bharath, J. Saini, R. Jamuna, J. Keshav Kumar, S.L. Rao, B.A. Chandramouli, S.K. Shankar, P. Satishchandra | 183-190 |
Role of NMDA receptors in noise-induced tau hyperphosphorylation in rat hippocampus and prefrontal cortex31 March 2014 Abstract: Chronic noise exposure has been associated with abnormalities in glutamate (Glu)-NMDAR signaling and tau hyperphosphorylation. However, further studies are necessary to clarify potential cau... |
Kang Li, Hengchuan Jia, Xiaojun She, Bo Cui, Na Zhang, Xuewei Chen, Chuanxiang Xu, Gaihong An, Qiang Ma | 191-197 |
Tyrosine hydroxylase expression and activity in nigrostriatal dopaminergic neurons of MPTP-treated mice at the presymptomatic and symptomatic stages of parkinsonism24 April 2014 Abstract: Progressive degeneration of nigrostriatal dopaminergic (DA-ergic) neurons is a key component in the pathogenesis of Parkinson's disease, which develops for a long time at the preclinical sta... |
Elena A. Kozina, Gulnara R. Khakimova, Vitaly G. Khaindrava, Valeriayn G. Kucheryanu, Nadezhda E. Vorobyeva, Alexey N. Krasnov, Sophia G. Georgieva, Lidiya Kerkerian-Le Goff, Michael V. Ugrumov | 198-207 |
Correlation between cerebral microbleeds and S100B/RAGE in acute lacunar stroke patients21 March 2014 Abstract: Background and purpose: S100B and its scavenger, soluble receptor for advanced glycation end products (sRAGE), participate in various acute and chronic brain disorders. However, their impact... |
Lulu Xiao, Wen Sun, Wenya Lan, Yunyun Xiong, Zuowei Duan, Zongjun Zhang, Wenping Fan, Lili Xu, Xia Xie, Nan Ma, Ruidong Ye, Gelin Xu, Xinfeng Liu, Wusheng Zhu | 208-212 |
Short Communications |
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| Article Title | Author(s) | Pages |
Atypical MRI features at early onset natalizumab-associated progressive multifocal leukoencephalopathy: A case report18 March 2014 Abstract: We report the case of a woman with natalizumab-treated Multiple Sclerosis (MS) that developed progressive multifocal leukoencephalopathy (PML) with atypical MRI features at early onset. This... |
Mirko Piola, Franco Di Palma, Nerina Mascoli, Sandro Binda, Marco Arnaboldi, Monica Rezzonico | 213-214 |
How does smoking affect olfaction in Parkinson's disease?21 March 2014 Abstract: Smoke-induced upper airway damage and Parkinson's disease (PD) can be considered independent risk factors for smell impairment. Interestingly, cigarette smoking has been strongly associated ... |
Marcello Moccia, Marina Picillo, Roberto Erro, Carmine Vitale, Marianna Amboni, Raffaele Palladino, Dante Luigi Cioffi, Paolo Barone, Maria Teresa Pellecchia | 215-217 |
An unusual cause of cerebellar ataxia in an immunocompromised elderly patient13 March 2014 Abstract: Background: Parvovirus B19 is a single-stranded DNA virus belonging to the family Parvoviridae, genus Erythrovirus. PVB19 infection is most common in the pediatric population, manifesting as... |
Sheetal Shroff, Carlos Kamiya-Matsuoka, Karin Woodman | 218-220 |
A novel XK gene mutation in a Taiwanese family with McLeod syndrome13 March 2014 Abstract: McLeod syndrome is one subtype of rare neuroacanthocytosis syndromes characterized by misshapen red blood cells and progressive degeneration of the basal ganglia. It is an X-linked recessive... |
Pei-Yun Chen, Szu-Chia Lai, Chih-Chao Yang, Ming-Jen Lee, Yen-Hui Chiu, Sui-Hing Yan, Chin-Song Lu, Tu-Hsueh Yeh | 221-224 |
Intra-arterial vasodilator therapy for parainfectious cerebral vasospasm21 March 2014 Abstract: Cerebrovascular complications of bacterial meningitis may include vasculitis, vasospasm or vasoconstriction, delayed cerebral infarction, venous and arterial thrombosis, intracranial aneurys... |
Ather Taqui, Lauren Koffman, Ferdinand Hui, Joao Gomes, M. Shazam Hussain, Mark Bain, Gabor Toth | 225-229 |
Adverse lipid profile is not associated with relapse risk in MS: Results from an observational cohort study20 March 2014 Abstract: Background: There is increasing evidence that serum lipids and apolipoproteins may be associated with multiple sclerosis (MS) clinical course. Objective: To investigate the associations betw... |
Prudence Tettey, Steve Simpson, Bruce Taylor, Leigh Blizzard, Anne-Louise Ponsonby, Terence Dwyer, Karam Kostner, Ingrid van der Mei | 230-232 |
Novel homozygous PANK2 mutation causing atypical pantothenate kinase-associated neurodegeneration (PKAN) in a Cypriot family20 March 2014 Abstract: Pantothenate kinase-associated neurodegeneration (PKAN) is the commonest, recessively inherited form of neurodegeneration with brain iron accumulation (NBIA) resulting from mutations in the ... |
George A. Tanteles, Elena Spanou-Aristidou, Chloe Antoniou, Violetta Christophidou-Anastasiadou, Kleopas A. Kleopa | 233-236 |
Letters to the Editor |
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| Article Title | Author(s) | Pages |
Uncommon foreign body reaction caused by derivation drain mimicking high grade CNS tumor13 March 2014 We report a case of a 40year old woman, who was hospitalized in our neuro-oncological unit for a suspicion of central nervous system tumor. At 3years old, she has a history of suprasellar pilocytic as... |
C. Lebrun, L. Mondot, V. Bourg, F. Burel-Vandenbos, D. Fontaine | 237-238 |
Corticosteroid-responsive torticollis as a presenting symptom of multiple sclerosis10 March 2014 Abstract: Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system that rarely presents with movement disorder symptoms upon primary manifestation. We report the ca... |
Benjamin Berger, Michel Rijntjes, Lena Stehlin, Oliver Stich | 239-240 |
Myelomatous meningitis: A rare neurological involvement in complete remission of Multiple Myeloma28 March 2014 Neurological manifestations of Multiple Myeloma (MM) are relatively common and often secondary to medullary compression, hypercalcemia, hyperviscosity or peripheral neuropathies . Leptomeningeal disse... |
Marisa Brum, Ana Santo António, Rui Guerreiro | 241-242 |
Cilostazol reduces morbidity but not mortality secondary to cerebral vasospasm following aneurysmal subarachnoid hemorrhage31 March 2014 I have read, with great interest, a recently published article in the Journal of the Neurological Sciences by Niu et al. titled 'Effect of cilostazol in patients with aneurysmal subarachnoid hemorrhag... |
Dale Ding | 243-244 |
Abadie's sign in adrenomyeloneuropathy14 April 2014 Highlights: |
Ryo Ohtomo, Takashi Matsukawa, Shoji Tsuji, Atsushi Iwata | 245-246 |
Book Review |
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| Article Title | Author(s) | Pages |
Book review11 April 2014 Neurovascular surgery is an ever-expanding field of neurosurgery. Not only have well-studied and validated techniques in open surgery been further refined over the last two decades, but the advent of ... |
Amandip S. Gill, Frank P.K. Hsu | 247 |
h of a transient ischemic attack 
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