Painful tic convulsif: Dual neurovascular compression within the spectrum of cranial nerve hyperactive dysfunction syndromes

Tariel Natsvaladze, Iago Tsertsvadze, Lika Burduli, Andrii Netliukh, Mario Ganau, Nana Tchantchaleishvili

• Article 100613
• https://doi.org/10.1016/j.ensci.2026.100613
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Abstract

This article reports a case of painful tic convulsif (concurrent trigeminal neuralgia and ipsilateral hemifacial spasm) successfully treated via microvascular decompression (MVD) of independent neurovascular conflicts involving the trigeminal and facial nerves. Accompanied by a literature review, the report emphasizes that single-session MVD targeting all responsible compression sites yields durable, symptom-free outcomes.

The effect of growth hormone-releasing hormone on cognition and brain connectivity in adults with cognition ranging from normal to mild cognitive impairment

Courtney E. Stewart, Kaci P. French, Traver J. Wright, Kayla Wilhoit, ... Brent E. Masel

• Article 100616
• https://doi.org/10.1016/j.ensci.2026.100616
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Abstract

In a double-blind, placebo-controlled pilot study of 22 adults with normal cognition to mild cognitive impairment, 10 weeks of low-dose tesamorelin (GHRH analog) showed no direct significant overall changes in primary clinical measures. However, advanced machine learning models identified treatment-related structural and functional brain changes in cognitive regions such as the right anterior cingulate and left superior frontal occipital fasciculus.

Correlation of the monocyte to high-density lipoprotein cholesterol ratio and neutrophil to high-density lipoprotein cholesterol ratio with the severity of acute ischemic stroke

Tahreem Sajjad, Iftikhar Haider, Alishba jaffery, Muhammad Ubaid

• Article 100617
• https://doi.org/10.1016/j.ensci.2026.100617
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Abstract

This cross-sectional study investigated inflammatory lipid ratios (MHR and NHR) in acute ischemic stroke (AIS) patients. Although MHR demonstrated a weak positive correlation with stroke severity on univariate analysis, it was not an independent predictor in multivariate models, suggesting it may serve as an accessible, low-cost indicator rather than an independent prognostic factor.

Associations of glycated hemoglobin with etiology, lesions, and outcome of ischemic stroke: Japan Stroke Data Bank

Shuhei Egashira, Kaori Miwa, Masatoshi Koga, Sohei Yoshimura, ... Kazunori Toyoda

• Article 100618
• https://doi.org/10.1016/j.ensci.2026.100618
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Abstract

Analyzing registry data from 13,569 acute ischemic stroke patients, this study found that higher admission HbA1c levels significantly correlated with a higher proportion of large artery atherosclerosis, a greater prevalence of brainstem lesions, and poorer overall functional outcomes at discharge.

Pharyngeal electrical stimulation for the treatment of dysphagia in Wallenberg syndrome: A FEES-based case analysis

Franziska Hinkelmann, Marcel Kaspari, Lars Wojtecki

• Article 100619
• https://doi.org/10.1016/j.ensci.2026.100619
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Abstract

In a single-case study of a 78-year-old woman with severe dysphagia following a dorsolateral medulla oblongata infarction (Wallenberg syndrome), 4 consecutive days of pharyngeal electrical stimulation (PES) via the Phagenyx® system led to significant recovery. Follow-up endoscopic evaluations demonstrated normal swallowing frequency, safe management of all tested consistencies, and a reduction in aspiration and secretion scores.