eNeurologicalScieNeurologicalSci Vol 1, Issue 2

June 2015 | Pages 20-46

Original Articles

Income in midlife and dementia related mortality over three decades: A Norwegian prospective study

Bjørn Heine Strand, Vegard Skirbekk, Tor A. Rosness, Knut Engedal, Espen Bjertness, for the GENIDEM-group

Studies on midlife income and dementia are scarce, and our main aim was to investigate midlife with later risk of dementia related mortality, adjusting for education and dementia related risk factors. The study population consisted of Norwegian men, aged 40–59 years in 1980 at income assessment, which participated in Norwegian health examination studies in the period 1980–2002 where risk factors such as cholesterol level, hypertension, smoking, cardiovascular disease, and diabetes were assessed. Dementia related mortality was defined as a dementia diagnosis on the death certificate until 2012.

Retinal nerve fiber layer sector-specific compromise in relapsing and remitting multiple sclerosis

Anette S. Loughran-Fjeldstad, Noel G. Carlson, Cassandra D. Husebye, Lawrence J. Cook, John W. Rose

To evaluate quadrant and sector retinal nerve fiber layer (RNFL) thickness and total macular volume (TMV) in relapsing–remitting multiple sclerosis (RR-MS) patients.

Cost and cost-effectiveness analysis of a bundled intervention to enhance outcomes after stroke in Nigeria: Rationale and design

Olanrewaju Olaniyan, Mayowa O. Owolabi, Rufus O. Akinyemi, Babatunde L. Salako, Samantha Hurst, Oyedunni Arulogun, Mulugeta Gebregziabher, Ezinne Uvere, Bruce Ovbiagele

The economic and social costs of stroke to the society can be enormous. These costs can cause serious economic damage to both the individual and the nation. It is thus important to conduct a cost effectiveness analysis to indicate whether an intervention provides high value where its health benefits justify its costs. This study will provide evidence based on the costs of stroke with a view of improving intervention and treatments of stoke survivors in Nigeria. This study utilizes two types of economic evaluation methods – cost-effectiveness analysis and cost–benefit analysis – to determine the economic impact of Tailored Hospital-based Risk Reduction to Impede Vascular Events after Stroke (THRIVES) intervention.


Short Communications

Pramipexole-induced antecollis in patients with Parkinson's disease: Two cases and literature review

Mutsumi Iijima, Mikio Osawa, Shinichiro Uchiyama, Kazuo Kitagawa

Antecollis is considered to be relatively rare in Parkinson's disease (PD). Few cases of dopamine agonist-induce antecollis in PD have been reported. We described literature review of 12 PD patients including our 2 cases with pramipexole (PPX)-induced antecollis. The patients were predominantly Japanese, women and above 3 of Hoehn and Yahr stage. PPX-induced antecollis in PD was considered a type of dystonia of flexor neck muscle, and was improved soon after cessation or reduction of PPX. Our two cases improved their antecollis by overnight changing from PPX to ropinirole without deteriorating motor functions.