Journal of the Neurological Sciences issue 440 now available

Reporting on neurological burden in Hargeisa, Somaliland between 2019 and 2020: A cross-sectional study

Abdulrahman et al.

Published online: June 23, 2022

Retrospective, cross-sectional study to characterise the disease burden of neurological cases in Hargeisa, Somaliland between January 2019 and June 2020 in order to shape clinical guidelines and develop policy interventions pertaining to brain health in the region.  Data was obtained from a case log of de-identified patients seen over an 18-month period. In addition, demographic data including age and gender for each patient was obtained and gender-specific significance for each disease was determined.

Prevalence and predictors of neurological manifestations in systemic AL amyloidosis

Thimm et al.

Published online: July 17, 2022

Immunoglobulin light chain (AL) amyloidosis is a life-threatening systemic disease due to plasma cell dyscrasias, which is characterized by amyloid deposition in various tissues. Neurological manifestations, in particular peripheral nervous system involvement, play a major role for quality of life and treatment decisions as frequently potentially neurotoxic drugs are used.

Full length article

Elucidation of peripheral nerve myelination by bimodal waveform analysis

Okuma et al.

Published online: July 19, 2022

As the myelin sheath of the peripheral nerves is immaturely developed in children, a bimodal waveform may be evoked when sensory nerve conduction studies are performed in them. However, there has been no study regarding the relationship between age and the frequency of appearance of the bimodal waveform or the inter-peak latency. Herein, we examined how the bimodal waveform changes with age.

Prevalence, predictors, and prognosis of mortality among elderly stroke patients with convulsive status epilepticus in the United States

Lekoubou et al.

Published online: July 17, 2022

Stroke is the most common cause of epilepsy in the elderly. However, despite the high mortality typically associated with convulsive status epilepticus (CSE), there is a dearth of nationwide data on the magnitude and association of CSE with mortality among hospitalized elderly with stroke in the United States.

While CSE occurs in just 14 of 10,000 hospitalized elderly stroke patients in the United States, it is associated with a 4-fold higher odds of in-hospital death.