JNS-cover.jpgJournal of Neurological Sciences

Vol 414 | 15 July 2020

Editorial

Hydroxychloroquine/ chloroquine as a treatment choice or prophylaxis for Covid-19 at the primary care level in developing countries: A Primum non Nocere dilemma

Marco T. Medina, Sir Salvador Moncada


Silencing of immune activation with methotrexate in patients with COVID-19

Farinaz Safavi, Avindra Nath

 

Review Articles

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Part I. SARS-CoV-2 triggered 'PANIC' attack in severe COVID-19

Elliot M. Frohman, Nicole R. Villemarette-Pittman, Esther Melamed, Roberto Alejandro Cruz, Reid Longmuir, Thomas C. Varkey, Lawrence Steinman, Scott S. Zamvil, Teresa C. Frohman


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Part II. high-dose methotrexate with leucovorin rescue for severe COVID-19: An immune stabilization strategy for SARS-CoV-2 induced 'PANIC' attack

Elliot M. Frohman, Nicole R. Villemarette-Pittman, Roberto Alejandro Cruz, Reid Longmuir, Vernon Rowe, Elizabeth S. Rowe, Thomas C. Varkey, Lawrence Steinman, Scott S. Zamvil, Teresa C. Frohman


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Novel fluid biomarkers to differentiate frontotemporal dementia and dementia with Lewy bodies from Alzheimer's disease: A systematic review

Aiysha Chaudhry, Henry Houlden, Mie Rizig


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Overview of sleep disturbances and their management in Parkinson plus disorders

Amitabh Bhattacharya, Abhishek Lenka, Albert Stezin, Nitish Kamble, Pramod Kumar Pal


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Beyond the brain: Extra-axial pathology on diffusion weighted imaging in neuroimaging

Dermot Mallon, Luke Dixon, Tom Campion, Gemma Dawe, Kunwar Bhatia, Carolina Kachramanoglou, Olga Kirmi

 

Basic Research Papers

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Impact of complete recanalization on clinical recovery in cardioembolic stroke patients with M2 occlusion

Junya Aoki, Kentaro Suzuki, Takuya Kanamaru, Takehiro Katano, Akihito Kutsuna, Yuki Sakamoto, Satoshi Suda, Yasuhiro Nishiyama, Naomi Morita, Masafumi Harada, Shinji Nagahiro, Kazumi Kimura


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Derivation of a bedside score (MASH-P) to predict 6-month mortality in tuberculous meningitis

Imran Rizvi, Hardeep Singh Malhotra, Ravindra Kumar Garg, Neeraj Kumar


Dysphagia in spinocerebellar ataxias type 1, 2, 3 and 6

Chen-Ya Yang, Ruo-Yah Lai, Nadia Amokrane, Chi-Ying Lin, Karla P. Figueroa, Stefan M. Pulst, Susan Perlman, George Wilmot, Christopher M. Gomez, Jeremy D. Schmahmann, Henry Paulson, Vikram G. Shakkottai, Liana S. Rosenthal, Sarah H. Ying, Theresa Zesiewicz, Khalaf Bushara, Michael Geschwind, Guangbin Xia, S.H. Subramony, Tetsuo Ashizawa, Michelle S. Troche, Sheng-Han Kuo


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Elevated cardio-ankle vascular index may be related to future stroke risk in Japanese subjects

Yasuhiro Nishiyama, Toshiaki Otsuka, Kanako Muraga, Katsuhito Kato, Yoshiyuki Saiki, Hiroshi Nagayama, Kazumi Kimura


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G6036A substitution in mitochondrial COX I gene compromises cytochrome c oxidase activity in thiamine responsive Leigh syndrome patients

Shalini Mani, S. Narasimha Rao, M.V. Kranthi Kumar


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Seasonal distribution of attacks in aquaporin-4 antibody disease and myelin-oligodendrocyte antibody disease

Giordani Rodrigues dos Passos, Liene Elsone, Sebastian Luppe, Joanna Kitley, Silvia Messina, Pedro María Rodríguez Cruz, Katharine Harding, Kerry Mutch, Maria Isabel Leite, Neil Robertson, Anu Jacob, Jacqueline Palace


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Primary cerebral lymphoma' characteristics, incidence, survival, and causes of death in the United States

Sherief Ghozy, Mahmoud Dibas, Ahmed M. Afifi, Mahmoud A. Hashim, Alzhraa Salah Abbas, Mohamed M. Abdel-Daim, Kevin Phan


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Efficacy and safety of 5-Hydroxytryptophan on levodopa-induced motor complications in Parkinson's disease: A preliminary finding

Mario Meloni, Monica Puligheddu, Fabrizio Sanna, Antonino Cannas, Rita Farris, Elisabetta Tronci, Michela Figorilli, Giovanni Defazio, Manolo Carta


Association of diabetes status with cognitive impairment in two Chinese rural communities

Mengyi Guo, Kaijiang Kang, Anxin Wang, Jiaokun Jia, Jia Zhang, Yu Wang, Dandan Wang, Shengyun Chen, Xingquan Zhao


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Improvement of a decreased anti-oxidative activity by edaravone in amyotrophic lateral sclerosis patients

Yasuyuki Ohta, Toru Yamashita, Emi Nomura, Nozomi Hishikawa, Ken Ikegami, Yosuke Osakada, Namiko Matsumoto, Yuko Kawahara, Taijun Yunoki, Yoshiaki Takahashi, Motonori Takamiya, Koh Tadokoro, Ryo Sasaki, Yumiko Nakano, Keiichiro Tsunoda, Kota Sato, Yoshio Omote, Mami Takemoto, Koji Abe


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The efficacy of perampanel as adjunctive therapy in drug-resistant focal epilepsy in a "real world" context: focus on temporal lobe epilepsy

Angelo Pascarella, Luigi Francesco Iannone, Giancarlo Di Gennaro, Alfredo D'Aniello, Edoardo Ferlazzo, Nazareno Gagliostro, Francesco Ursini, Paolo Bonanni, Nicola Paciello, Andrea Romigi, Umberto Aguglia, Giovambattista De Sarro, Emilio Russo, Antonio Gambardella, Angelo Labate


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The course of cerebrospinal fluid parameters ≤ 20 days after aneurysmal subarachnoid hemorrhage

Inez Koopman, Nicolaas P.A. Zuithoff, Gabriel J.E. Rinkel, Mervyn D.I. Vergouwen


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Association of matrix metalloproteinase-9 polymorphism with severity of Guillain-Barré syndrome

Shoma Hayat, Oyishee Ahmad, Ishtiaq Mahmud, Md. Zakir Hossain Howlader, Zhahirul Islam


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Diagnosis of paraproteinemic neuropathy: Room for improvement

Chafic Karam, Orly Moshe-Lilie, Nizar Chahin, Thomas Ragole, Eva Medvedova, Rebecca Silbermann


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Parcellation-based modeling of the dorsal premotor area

John R. Sheets, Robert G. Briggs, Michael Y. Bai, Anujan Poologaindran, Isabella M. Young, Andrew K. Conner, Cordell M. Baker, Chad A. Glenn, Michael E. Sughrue


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A new simple method using carotid duplex ultrasonography to assess intracranial vertebrobasilar arterial stenosis

Kosuke Matsuzono, Kohei Furuya, Takafumi Mashiko, Tadashi Ozawa, Kumiko Miura, Masayuki Suzuki, Misato Ozawa, Haruo Shimazaki, Reiji Koide, Ryota Tanaka, Shigeru Fujimoto


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Effect of cognitive rehabilitation on neuropsychological and semiecological testing and on daily cognitive functioning in multiple sclerosis: The REACTIV randomized controlled study

D. Lamargue, I. Koubiyr, M. Deloire, A. Saubusse, J. Charre-Morin, A. Moroso, P. Coupé, B. Brochet, A. Ruet


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Accumulation of HAX-1 and PARL in brainstem- and cortical-type Lewy bodies in Parkinson's disease and dementia with Lewy bodies

Yasuhiro Kawamoto, Takashi Ayaki, Makoto Urushitani, Hidefumi Ito, Ryosuke Takahashi


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Microstructural white matter changes following gait training with Hybrid Assistive Limb initiated within 1 week of stroke onset

Daisuke Ando, Chiaki Yokota, Kazuhiro Koshino, Fumihiko Yasuno, Takeo Sato, Akihide Yamamoto, Hirotaka Odani, Takashi Nakajima, Takahiro Higuchi, Eisuke Tatsumi


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Differential effects of thyrotropin releasing hormone (TRH) on motor execution and motor adaptation process in patients with spinocerebellar degeneration

Takahiro Shimizu, Ryosuke Tsutsumi, Kazutaka Shimizu, Naomi Tominaga, Makiko Nagai, Yoshikazu Ugawa, Kazutoshi Nishiyama, Ritsuko Hanajima


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Assessment of the reporting quality of double-blind RCTs for ischemic stroke based on the CONSORT statement

Michalis Kodounis, Ioannis N. Liampas, Theodoros S. Constantinidis, Vasileios Siokas, Alexios-Fotios A. Mentis, Athina-Maria Aloizou, Georgia Xiromerisiou, Elias Zintzaras, Georgios M. Hadjigeorgiou, Efthimios Dardiotis


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Pneumonia risk and its associated factors in Parkinson's disease: A National Database Study

Jun Hee Won, Seong Jun Byun, Byung-Mo Oh, Han-Joon Kim, Sang Jun Park, Han Gil Seo


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The SUN test of vision: Investigation in healthy volunteers and comparison to the mobile universal lexicon evaluation system (MULES)

Natalie Dahan, Nicholas Moehringer, Lisena Hasanaj, Liliana Serrano, Binu Joseph, Shirley Wu, Rachel Nolan-Kenney, John-Ross Rizzo, Janet C. Rucker, Steven L. Galetta, Laura J. Balcer


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Development of a clinical score, PANDA, to predict delirium in stroke care unit

Tomoki Nakamizo, Toshie Kanda, Yosuke Kudo, Eriko Sugawara, Erina Hashimoto, Ayana Okazaki, Makoto Usuda, Toru Nagai, Hiroshi Hara, Ken Johkura


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An automated alert system based on the p-Tau/Tau ratio to quickly inform health professionals upon a suspected case of sporadic Creutzfeldt-Jakob disease.

Laura Foucault-Fruchard, Jean Baptiste Delaye, Virginie Morange, Emilie Beaufils, Coline Duwicquet, Isabelle Quadrio, Anna Chloé Balageas, Diane Dufour-Rainfray


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Transcranial Doppler velocity and associations with delayed cerebral ischemia in aneurysmal subarachnoid Hemorrhage

Jason J. Chang, Matthew Triano, Maite J. Corbin, Sameer Desale, Ai-Hsi Liu, Daniel R. Felbaum, Jeffrey C. Mai, Rocco A. Armonda, Edward F. Aulisi


Neurological manifestations and COVID-19: Experiences from a tertiary care center at the Frontline

Pranusha Pinna, Parneet Grewal, Julianne P. Hall, Tachira Tavarez, Rima M. Dafer, Rajeev Garg, Nicholas D. Osteraas, Danielle R. Pellack, Anjali Asthana, Kelsey Fegan, Vikram Patel, James J. Conners, Sayona John, Ivan Da Silva


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ADC values of benign and high grade meningiomas and associations with tumor cellularity and proliferation – A systematic review and meta-analysis

Hans-Jonas Meyer, Andreas Wienke, Alexey Surov


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Frequency and factors linked to refractory hypertension among stroke survivors in Ghana

Fred Stephen Sarfo, John Akassi, Sheila Adamu, Vida Obese, Manolo Agbenorku, Bruce Ovbiagele


Real world application of ocrelizumab in multiple sclerosis: Single-center experience of 128 patients

Victoria Prockl, Florian T. Nickel, Kathrin S. Utz, Kilian Fröhlich, Tobias Engelhorn, Max-Josef Hilz, De-Hyung Lee, Ralf A. Linker, Konstantin Huhn

 

Clinical Short Communications

Wearing-off at the end of natalizumab dosing interval and risk of MS disease activity: A prospective 1-year follow-up study

Gerd Haga Bringeland, Kjell-Morten Myhr, Christian Alexander Vedeler, Sonia Gavasso


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Choroid plexus changes on magnetic resonance imaging in multiple sclerosis and neuromyelitis optica spectrum disorder

Hyunjin Kim, Young-Min Lim, Geonwoo Kim, Eun-Jae Lee, Jeong Hyun Lee, Hye Weon Kim, Kwang-Kuk Kim


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Expanding the cerebrovascular phenotype of the p.R258H variant in ACTA2 related hereditary thoracic aortic disease (HTAD)

Birgitte Rode Diness, Rachel Nina Palmquist, Rikke Norling, Hanne Hove, Henning Bundgaard, Jens Michael Hertz, Daniel Kondziella, Derk Krieger, Morten Dunø, Sabine Grønborg


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Novel dot-blot assay for detection of vascular Notch3 aggregates in patients with CADASIL

Yihong Ma, Mitsuharu Ueda, Akihiko Ueda, Satoru Shinriki, Akihito Nagatoshi, Aito Isoguchi, Masamitsu Okada, Masayoshi Tasaki, Toshiya Nomura, Yasuteru Inoue, Teruaki Masuda, Yohei Misumi, Taro Yamashita, Hirotaka Matsui, Yukio Ando


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Valproate impact and sex-dependent seizure remission in patients with idiopathic generalized epilepsy

Emanuele Cerulli Irelli, Enrico Cocchi, Alessandra Morano, Sara Casciato, Martina Fanella, Mariarita Albini, Giacomo Fisco, Francesca A. Barone, Biagio Orlando, Addolorata Mascia, Mario Manfredi, Jinane Fattouch, Anna T. Giallonardo, Giancarlo Di Gennaro, Carlo Di Bonaventura

 

Letters to the Editor

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TTN missense variants in two siblings with asymmetric facial and limb weakness

Ryo Sasaki, Yasuyuki Ohta, Koh Tadokoro, Namiko Matsumoto, Emi Nomura, Yoshio Omote, Mami Takemoto, Nozomi Hishikawa, Toru Yamashita, Theerawat Kumutpongpanich, Ichizo Nishino, Koji Abe


Semantic fluency and cognitive function impairment in multiple sclerosis patients

Syed Ijlal Ahmed, Nisha Lohana, Gohar Javed, Syeda Beenish Bareeqa, Syeda Sana Samar, Syed Hasham Humayun


Elderly patient with 5q spinal muscular atrophy type 4 markedly improved by Nusinersen

Teruya Morizumi, Akihiro Ueno, Ken Takasone, Kazuki Ozawa, Tsuneaki Yoshinaga, Katsuya Nakamura, Yoshiki Sekijima


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Ventriculoperitoneal shunt-related intracranial hypotension mimicking brainstem encephalitis

Sang Bin Hong, Yong-Won Shin, Sang Kun Lee


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Novel CACNA1A variant may cause cervical dystonia and cerebellar ataxia syndrome

A. Fuerte-Hortigón, R. Pérez-Noguera, J. Dotor García-Soto, I. Royo Boronat, S. Álvarez de Andrés, J.M. García-Moreno


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COVID-19-associated mild encephalitis/encephalopathy with a reversible splenial lesion

Misayo Hayashi, Yuki Sahashi, Yasutomo Baba, Hiroyuki Okura, Takayoshi Shimohata


Serotonin syndrome in two COVID-19 patients treated with lopinavir/ritonavir

Miguel Mas Serrano, Javier Ricardo Pérez-Sánchez, Sofía Portela Sánchez, Beatriz De La Casa-Fages, Víctor Mato Jimeno, Isabel Pérez Tamayo, Francisco Grandas


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COVID-19-associated delayed posthypoxic necrotizing leukoencephalopathy

Alireza Radmanesh, Anna Derman, Koto Ishida