Unexpected infectious complication following AVM embolization: E. coli brain abscess

Andrii Netliukh, Andrian Sukhanov, Nana Tchantchaleishvili

• Article number: 100594
• https://doi.org/10.1016/j.ensci.2022.100594
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Abstract

Brain arteriovenous malformations (AVMs) are rare vascular anomalies managed with surgery, radiosurgery, or endovascular embolization. Post-embolization intracranial infections are extremely uncommon, especially Escherichia coli abscesses in immunocompetent adults. We report a 37-year-old man with a giant left frontal AVM treated with staged Onyx® embolization. One month after the final session, he developed a left frontal brain abscess with motor aphasia and right-sided hemiparesis. Cultures grew hemolytic E. coli sensitive to multiple antibiotics.

Association between DATSCAN-derived dopaminergic activity and cognitive performance and quality of life in Parkinson's disease: A cross-sectional study

Farzaneh Ramezani, SeyedAli Mahmoudi, Faezeh Safari

• Article number: 100599
• https://doi.org/10.1016/j.ensci.2022.100599
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Abstract

Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor and non-motor symptoms that substantially affect quality of life (QoL). This study investigated associations between dopaminergic activity, measured via DATSCAN imaging, and clinical outcomes including cognitive performance, mobility, and QoL. Results showed no significant associations with cognitive performance or QoL, and only modest correlations with mobility measures, highlighting the multifactorial nature of PD.

Factors associated with the progression of disability (EDSS) among MS patients

Anibal Arteaga-Noriega, Jose Zapata-Berruecos, Johanna Gutiérrez-Vargas, John Camilo Garcia, ... Manuela Restrepo-Botero

• Article number: 100602
• https://doi.org/10.1016/j.ensci.2022.100602
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Abstract

Multiple sclerosis is a chronic, inflammatory, autoimmune disease of the central nervous system. The aim of this study was to analyze the disability trajectory across years of patients living with MS seen at the Neurological Institute. Disability measured by the EDSS was not linear over time. Multivariate models showed that clinical and sociodemographic variables such as initial cerebellar symptoms and sex had the highest significant impact on disability progression.

Postpartum watershed strokes as initial manifestation of a rare co-occurrence of systemic lupus erythematosus and Takayasu Vasculitis: A case report of neuroimmunologic and literature review

Cédric Agbo-Panzo, Kadjo Cédric Kadjo, Chubaka Magala Gloire, Nancy Essoin, ... B. Assi

• Article number: 100597
• https://doi.org/10.1016/j.ensci.2025.100597
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Hypertensive brainstem encephalopathy with isolated headache and blurred vision: A case report

Seo-Young Choi, Jae-Hwan Choi, Kwang-Dong Choi

• Article number: 100600
• https://doi.org/10.1016/j.ensci.2022.100600
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Abstract

A 41-year-old man presented with acute severe headache, vomiting, and blurred vision with a blood pressure of 200/130 mmHg. Brain MRI demonstrated asymmetric hyperintensities in the brainstem, consistent with hypertensive brainstem encephalopathy (HBE). Early recognition through neuroimaging and prompt blood pressure management resulted in rapid symptom resolution and complete recovery of brainstem lesions.

Identification of myokymia in adult-onset hereditary spastic paraplegia type 79A: Implications for the phenotypic spectrum

Natsumi Toyoda, Hiroyasu Komiya, Yosuke Miyaji, Shuhei Nishihama, ... Fumiaki Tanaka

• Article number: 100603
• https://doi.org/10.1016/j.ensci.2022.100603
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Abstract

Spastic paraplegia type 79 (SPG79) is a rare form of hereditary spastic paraplegia. We report the first documented case of myokymia in SPG79A (late-onset autosomal dominant form) in a 74-year-old man. Genetic testing identified a heterozygous nonsense variant in UCHL1. This case suggests that myokymia, though rare in hereditary spastic paraplegias, can occur in SPG79A and may serve as a diagnostic clue.