JNS.jpgThe March issue of the Journal of the Neurological Sciences Vol 470 is now available online.

 

Click here to access

 

Issue highlights

gr1.sml Review Article | Open Access

Comparative outcomes of endovascular vs. surgical treatment in craniocervical junction dural arteriovenous fistulas: A systematic review and meta-analysis

Musmar et al.

Published online: January 21, 2025

 

Craniocervical junction dural arteriovenous fistulas (CCJ-DAVFs) are rare and complex vascular malformations that are challenging to diagnose and treat. This study aims to compare surgical and endovascular treatments for CCJ-DAVFs through a systematic review and meta-analysis.

A systematic review and meta-analysis was conducted according to the PRISMA guidelines. PubMed, Scopus, and Web of Science databases were searched from inception to July 2024.


gr1.sml Research Article

HIV-associated neurocognitive disorders (HAND): Optimal diagnosis, antiviral therapy, pharmacological treatment, management, and future scopes

Adhikary et al.

Published online: January 29, 2025

 

In the context of HIV infection, HIV-associated neurocognitive disorders (HAND) have become a serious concern. An extensive summary of the diagnosis, care, and mental health consequences related to HAND is given in this article. The diagnosis of HAND entails a multimodal approach that includes neuroimaging, cognition tests, and clinical examinations. Numerous screening instruments and standardized evaluations have been created to support the early identification and tracking of HAND...


gr1.sml Research Article | Open Access

Usefulness of serum neurofilament light chain in chronic inflammatory demyelinating polyradiculoneuropathy

Llauradó et al.

Published online: January 18, 2025

 

The development of new biomarkers is essential to improve diagnostic accuracy and guide treatment decisions in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). The aim of this study was to investigate the utility of the serum neurofilament light chain (sNfL) level as a marker for disability and response to immunomodulatory treatment in patients with CIDP.

This prospective, single-center, observational study included 38 patients with CIDP: 19 treatment-naive (CIDP-I) patients assessed before and after the initiation of immunomodulatory therapy and 19 stable patients on maintenance immunoglobulins (CIDP-M). Clinical scales (INCAT, I-RODS, MRC-SS and grip strength) were used to assess disability and treatment response. Nerve conduction study data were collected.


Research Article | Open Access

Health challenges of climate change in the Eastern Mediterranean and Middle East region, with a focus on Türkiye. An environmental neurological and brain health perspective

Reis et al.

Published online: February 10, 2025

 

The Eastern Mediterranean and Middle East region, where both natural and anthropogenic disasters have occurred, is particularly vulnerable to the effects of climate change. This article aims to alert and inform the neurological community about the many health risks linked to climate change, including some more specific ones, such as the mucilage phenomenon, heat waves and dust storms, and the spread of vector-borne infections. We describe the potential adverse effects of such climate-related exposures and advocate for more research to promote Brain Health.