JNS.jpgThe January issue of the Journal of the Neurological Sciences Vol 420 is now available online.


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Issue highlights

Stroke-related delirium

  • Delirium is a common stroke complication.
  • Delirium is a serious condition that can interfere with the prognosis of stroke.
  • Uncomfortable care modalities (prohibited self-transfer, nighttime care) may induce stroke related delirium.

Innovation in resident education – Description of the Neurology International Residents Videoconference and Exchange (NIRVE) program

There is considerable heterogeneity in residency education around the world. The Neurology International Residents Videoconference and Exchange (NIRVE) program aims to deliver neurology educational content to residents across different resource settings and countries through a monthly videoconferencing platform. NIRVE also facilitates resident exchanges among participating sites. In this descriptive article, we report NIRVE's structure and its cumulative productivity.

Since its creation, NIRVE has held more than 90 videoconference rounds and has connected 16 sites in North America, South America, Europe, Asia and Africa We describe challenges encountered since the inception of the program eleven years ago.

NIRVE also fosters a culture of long-term international connection and collaboration. During global disease outbreaks, such as the current COVID-19 pandemic, videoconference rounds serve as a sustainable alternative means to deliver education. Future goals include increasing the number of sites involved, including a focus on Africa and Asia, and fostering resident-led advocacy projects.

Cerebral micro-infarcts; the hidden missing link to vascular cognitive decline

Cerebral micro-infarcts (CMI) are small lesions of presumed ischemic etiology that cannot be visualized by the naked eye of the pathologist. They are probably the most common type of ischemic insult to the brain tissue in the elderly in general and in patients with either dementia or vascular risk factors in particular. Unfortunately, due to their small size and asymptomatic nature, they can be easily overlooked by neuroradiologists.

Despite their small size, CMI are believed to play a major role in an ongoing process of disruption of the structural integrity. Thus, previous studies that evaluated the local effect of small asymptomatic CMI using longitudinal structural and diffusion tensor imaging showed chronic local microstructural injury to white matter tracts.

Guillain Barré Syndrome and its variants as a manifestation of COVID-19: A systematic review of case reports and case series

The COVID-19 pandemic caused by SARS-COV-2 began in Wuhan, China in December 2019. Reports of COVID-19 with central (CNS) and peripheral nervous (PNS) system manifestations are emerging.

In this systematic review, we compared and summarized the demographics, clinical features, Brighton criteria, immunological and laboratory findings with a focus on modified Erasmus GBS Outcome Score (mEGOS) in SARS-CoV-2 patients with GBS and its variants.

  • Majority of GBS variants in COVID-19 patients were AIDP.
  • Most AIDP, AMAN/AMSAN patients exhibited Brighton level 1-maximum diagnostic certainty.
  • The mean latency between COVID-19 infection and GBS ranged between 11 and 13 days.